In addition to reversing abnormal keratinization, there is evidence that the topical retinoids may have some anti-inflammatory properties. Both adapalene (Differin®) and tretinoin have been shown to do this in different experiments. Because Retin-A has been on the market for more than 25 years, patients will frequently come in and say, "I've already used tretinoin; it didn't work." For many physicians, their first inclination is to try something else. My favorite therapy is a topical retinoid used in conjunction with a combination of benzoyl peroxide and erythromycin.
Topical antimicrobial agents are effective in the treatment of inflammatory disease. Benzoyl peroxide is a bactericide and is an excellent first-line medication. The response to this agent is rapid, with improvement noted as early as five days after treatment has begun, but irritation is common. Water-based products, as compared with alcohol based products, when used at low peroxide concentrations (5 to 5 percent) will help to limit this problem and have an efficacy similar to that of other products in this class. Benzoyl peroxide does not induce resistance; when used with topical or oral antibiotics, it protects against the development of this problem.
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tags: home remedy to remove acne scars, top acne medications, use of neem juice on skin care as anti acne
